รศ.ดร.ภญ.ลัดดาวัลย์ เส็งกันไพร

Publication

Scopus Author Profile

International Publication

• Pocasap P, Kongpetch S, Prawan A, Kaimuangpak K, Senggunprai L. Identification of Prognostic Factors in Esophageal Cancer Using Machine Learning: A Retrospective Study Based on the SEER Database. Journal of Clinical Medicine. 2026;15(8).
• Choonong R, Senggunprai L, Putalun W, Phoolcharoen W. Quantification of cucurbitacins B and E in Coccinia grandis fruit ethanolic extract and their anti-inflammatory effects in SARS-CoV-2 protein-stimulated macrophages. Cogent Food and Agriculture. 2026;12(1).
• Buranrat B, Sa-Ngiamwibool P, Prawan A, Kongpetch S, Pocasap P, Senggunprai L. Repurposing Rosiglitazone Induces Apoptosis Accompanied by Impaired Antioxidant Defense in Cholangiocarcinoma Cells: Findings from Proteomic and Functional Analyses. Pharmaceuticals. 2026;19(1).
• Pocasap P, Kaimuangpak K, Phukmee K, Prawan A, Kongpetch S, Senggunprai L. Unveiling the Anticancer Potential and Molecular Mechanisms of Fangchinoline Against Cholangiocarcinoma Using FTIR Microspectroscopy, In Vitro and In Silico Approaches. Integr Cancer Ther 2025; 24: 15347354251396513.
• Sa-Ngiamwibool P, Yoshinari K, Shizu R, Kongpetch S, Prawan A, Senggunprai L. Expression and Prognostic Implication of the Nuclear Receptors Farnesoid X Receptor and Pregnane X Receptor in Human Cholangiocarcinoma. Cancer Diagn Progn 2025; 5: 529-541.
• Jaidee R, Pocasap P, Jusakul A, Senggunprai L, Prawan A, Hong JH, Heng HL, Kukongviriyapan V, Teh BT, Kongpetch S. Synergistic suppression of cholangiocarcinoma cells via DNA damage response and cell cycle arrest by dual targeting PARP and ATM in DNA damage repair pathway. Biomedicine and Pharmacotherapy 2025 Jun 18; 189: 118273.
• Jaidee R, Jusakul A, Pocasap P, Kukongviriyapan V, Senggunprai L, Prawan A, Loilome W, Titapun A, Jareanrat A, Thanasukarn V, Khuntikeo N, Namwat N, Chamgramol Y, Thanee M, Wichian P, Hong JH, Guan P, Heng HL, Pairojkul C, Teh BT, Kongpetch S. Establishment and genomic profiling of cholangiocarcinoma cells with functional characterization. Sci Rep 2025 Mar 13; 15: 8621; Published online.
• Buranrat B, Senggunprai L, Prawan A, Kukongviriyapan V. Fisetin-induced cell death, apoptosis, and antimigratory effects in cholangiocarcinoma cells. Journal of Applied Pharmaceutical Science. 2025 Jan 5; 15(2):96-105.
• Pocasap P, Prawan A, Kongpetch S, Senggunprai L. Network pharmacology- and cell-based assessments identify the FAK/Src pathway as a molecular target for the antimetastatic effect of momordin Ic against cholangiocarcinoma. Heliyon. 2024 June; 10: e32352.
• Mahaamnad N, Pocasap P, Kukongviriyapan V, Senggunprai L, Prawan A, Kongpetch S. Dual blockage of PI3K-mTOR and FGFR induced autophagic cell death in cholangiocarcinoma cells. Heliyon. 2024 May; 10: e31112.
• Oeurn K, Jusakul A, Jaidee R, Kukongviriyapan V, Senggunprai L, Prawan A, Kongpetch S. FGF10/FGFR2 Signaling: Therapeutically Targetable Vulnerability in Ligand-responsive Cholangiocarcinoma Cells. In Vivo. 2023 Jul-Aug;37(4):1628-1637.
• Singdam P, Naowaboot J, Senggunprai L, Boonloh K, Hipkaeo W, Pannangpetch P. The Mechanisms of Neochlorogenic Acid (3-Caffeoylquinic Acid) in Improving glucose and Lipid Metabolism in Rats with Insulin Resistance Induced by A High Fat-High Fructose Diet. Trends in Sciences. 2023 Mar 1; 20(3): 6455.
• Malikrong P, Prawan A,Kongpetch S, Senggunprai L. Momordin ic triggers mitochondria-mediated apoptosis of cholangiocarcinoma cells and enhances the efficacy of conventional chemotherapeutic drugs. Farmacia. 2023 Feb;71(3):518–525.
• Butsri S, Kukongviriyapan V, Senggunprai L, Kongpetch S, Prawan A. 13-cis-retinoic acid inhibits the self-renewal, migration, invasion and adhesion of cholangiocarcinoma cells. Int J Mol Med 2023; 51. Published online 2023 Jan 21.
• Buranrat B, Senggunprai L, Prawan A, Kukongviriyapan V. Piperine Induces Cell Death, Apoptosis and Inhibits Migration in Cholangiocarcinoma Cells. Indian Journal of Pharmaceutical Education and Research. 2023 Jan-Mar; 57(1):161-166.
• Singdam P, Naowaboot J, Senggunprai L, Boonloh K, Pannangpetch P. Pluchea indica Leaf Extract Alleviates Dyslipidemia and Hepatic Steatosis by Modifying the Expression of Lipid Metabolism-Related Genes in Rats Fed a High Fat-High Fructose Diet. Preventive Nutrition and Food Science. 2022 Dec; 27(4): 384-398.
• Kaewmeesri P, Pocasap P, Kukongviriyapan V, Prawan A, Kongpetch S, Senggunprai L. Anti-metastatic Potential of Natural Triterpenoid Cucurbitacin B Against Cholangiocarcinoma Cells by Targeting Src Protein. Integr Cancer Ther 2022 Sep 27; 21: 15347354221124861.
• Thongrung R, Senggunprai L, Hipkaeo W, Tangsucharit P, Pannangpetch P. Anti-angiogenesis and anti-inflammatory effects of Moringa oleifera leaf extract in the early stages of streptozotocin-induced diabetic nephropathy in rats. Asian Pacific Journal of Tropical Biomedicine. 2022 Jul 20;12(7):290-299.
• Senggunprai L, Kukongviriyapan V, Prawan A, Kongpetch S. Epidermal growth factor receptor as a potential target of momordin Ic to promote apoptosis of cholangiocarcinoma cells. J Pharm Pharmacol . 2022 Jul 15;74(7):996-1005.
• Butsri S, Kukongviriyapan V, Senggunprai L, Kongpetch S, Prawan A. All-trans-retinoic acid induces RARB-dependent apoptosis via ROS induction and enhances cisplatin sensitivity by NRF2 downregulation in cholangiocarcinoma cells. Oncol Lett. 2022 Jun;23(6):179.
• Jaidee R, Kukongviriyapan V, Senggunprai L, Prawan A, Jusakul A, Laphanuwat P, Kongpetch S. Inhibition of FGFR2 enhances chemosensitivity to gemcitabine in cholangiocarcinoma through the AKT/mTOR and EMT signaling pathways. Life Sci. 2022 May 1; 296: 120427.
• Buranrat B, Senggunprai L, Prawan A, Kukongviriyapan V. Effects of Simvastatin in Combination with Anticancer Drugs on Proliferation and Migration in Cholangiocarcinoma Cells. Indian J Pharm Sci 2022 Jan 17;84(1):72-79.
• Laphanuwat P, Kongpetch S, Senggunprai L, Prawan A, Kukongviriyapan V. Licochalcone A Induces Cholangiocarcinoma Cell Death Via Suppression of Nrf2 and NF-kappaB Signaling Pathways. Asian Pac J Cancer Prev. 2022 Jan 1; 23: 115-123.

National Publication

• Andreani PR, Senggunprai L, Kongpetch S, Pocasap P, Yenjai C, Supakorn A, Prawan A. In vitro inhibition of migration and adhesion in cholangiocarcinoma cells by ovalitenin A through PI3K modulation. Journal of Basic and Applied Pharmacology. 2026 Feb 16. [Epub ahead of print].
• จิราพร จินดาพล, บงกชพร บุญเหลือ, ปรเมศ พลดงนอก, พาณิภัค สิริเพาประดิษฐ์, สิริวรรธน์ จิระอานนท์, กฤติยา ภักมี, ลัดดาวัลย์ เส็งกันไพร. ศักยภาพในการต้านมะเร็งของสารสกัดใบมะรุมด้วยนํ้าต่อเซลล์มะเร็งท่อนํ้าดีของมนุษย์. Health Science, Science and Technology Reviews. 2024 Sep- Dec;17(3):32-42.