Scopus Author Profile

รศ.ดร.ภญ.เอื้อมเดือน ประวาฬ

Assoc. Prof. Auemduan Prawan

Research Interest :

• Pharmacodynamics of phytochemicals
• Redox modulation of antioxidant and antiinflammatory signaling
• Roles of phytochemicals in cancer prevention and chemotherapy

Email : peuamd@kku.ac.th

Publication (Last 5 years : 2020-2024)

    International Publication

• Pocasap P, Prawan A, Kongpetch S, Senggunprai L. Network pharmacology- and cell-based assessments identify the FAK/Src pathway as a molecular target for the antimetastatic effect of momordin Ic against cholangiocarcinoma. Heliyon. 2024 June; 10: e32352.
  
• Mahaamnad N, Pocasap P, Kukongviriyapan V, Senggunprai L, Prawan A, Kongpetch S. Dual blockage of PI3K-mTOR and FGFR induced autophagic cell death in cholangiocarcinoma cells. Heliyon. 2024 May; 10: e31112.
  
• Oeurn K, Jusakul A, Jaidee R, Kukongviriyapan V, Senggunprai L, Prawan A, Kongpetch S. FGF10/FGFR2 Signaling: Therapeutically Targetable Vulnerability in Ligand-responsive Cholangiocarcinoma Cells. In Vivo. 2023 Jul-Aug;37(4):1628-1637.
  
• Arthan S, Yenjai C, Pornchoo C, Prawan A. Chemical constituents from the branches of Millettia brandisiana and their biological activities. Phytochemistry Letters. 2023 Feb :53;222-225.
  
• Sombatsri A, Sribuhom T, Pornchoo C, Prawan A, Yenjai C. Five new quinoline alkaloids from Sauropus hirsutus Beille and their cytotoxicity. Nat Prod Res. 2023 Feb;37(3):361-368.
  
• Malikrong P, Prawan A,Kongpetch S, Senggunprai L. Momordin ic triggers mitochondria-mediated apoptosis of cholangiocarcinoma cells and enhances the efficacy of conventional chemotherapeutic drugs. Farmacia. 2023 Feb;71(3):518–525.
  
• Butsri S, Kukongviriyapan V, Senggunprai L, Kongpetch S, Prawan A. 13-cis-retinoic acid inhibits the self-renewal, migration, invasion and adhesion of cholangiocarcinoma cells. Int J Mol Med 2023; 51. Published online 2023 Jan 21.
  
• Buranrat B, Senggunprai L, Prawan A, Kukongviriyapan V. Piperine Induces Cell Death, Apoptosis and Inhibits Migration in Cholangiocarcinoma Cells. Indian Journal of Pharmaceutical Education and Research. 2023 Jan-Mar; 57(1):161-166.
  
• Kaewmeesri P, Pocasap P, Kukongviriyapan V, Prawan A, Kongpetch S, Senggunprai L. Anti-metastatic Potential of Natural Triterpenoid Cucurbitacin B Against Cholangiocarcinoma Cells by Targeting Src Protein. Integr Cancer Ther 2022 Sep 27; 21: 15347354221124861.
  
• Senggunprai L, Kukongviriyapan V, Prawan A, Kongpetch S. Epidermal growth factor receptor as a potential target of momordin Ic to promote apoptosis of cholangiocarcinoma cells. J Pharm Pharmacol . 2022 Jul 15;74(7):996-1005.
  
• Butsri S, Kukongviriyapan V, Senggunprai L, Kongpetch S, Prawan A. All-trans-retinoic acid induces RARB-dependent apoptosis via ROS induction and enhances cisplatin sensitivity by NRF2 downregulation in cholangiocarcinoma cells. Oncol Lett. 2022 Jun;23(6):179.
  
• Jaidee R, Kukongviriyapan V, Senggunprai L, Prawan A, Jusakul A, Laphanuwat P, Kongpetch S. Inhibition of FGFR2 enhances chemosensitivity to gemcitabine in cholangiocarcinoma through the AKT/mTOR and EMT signaling pathways. Life Sci. 2022 May 1; 296: 120427.
  
• Sribuhom T, Posri P, Khankeaw W, Pornchoo C, Prawan A, Tontapha S, Amornkitbamrung V, Yenjai C . A rare isoflavone-quinone and a new flavanone from the roots of Dalbergia stipulacea Roxb. Nat Prod Res 2022 Mar 17: 1-9.
  
• Arthan S, Pornchoo C, Prawan A, Tontapha S, Amornkitbamrung V, Yenjai C. Brandisianones F and G from Millettia brandisiana Kurz and their cytotoxicity. Nat Prod Res. 2022 Mar;36(5):1236-1244.
  
• Buranrat B, Senggunprai L, Prawan A, Kukongviriyapan V. Effects of Simvastatin in Combination with Anticancer Drugs on Proliferation and Migration in Cholangiocarcinoma Cells. Indian J Pharm Sci 2022 Jan 17;84(1):72-79.
  
• Laphanuwat P, Kongpetch S, Senggunprai L, Prawan A, Kukongviriyapan V. Licochalcone A Induces Cholangiocarcinoma Cell Death Via Suppression of Nrf2 and NF-kappaB Signaling Pathways. Asian Pac J Cancer Prev. 2022 Jan 1; 23: 115-123.
  
• Wandee J, Srinontong P, Prawan A, Senggunprai L, Kongpetch S, Yenjai C, Kukongviriyapan V. Derrischalcone suppresses cholangiocarcinoma cells through targeting ROS-mediated mitochondrial cell death, Akt/mTOR, and FAK pathways. Naunyn Schmiedebergs Arch Pharmacol. 2021 Sep;394(9):1929-1940.
  
• Phusrisom S, Senggunprai L, Prawan A, Kongpetch S, Kukongviriyapan U, Thawornchinsombut S, Siriamornpun S, Chumroenphat T, Changsri R, Kukongviriyapan V. Anti-tumor activity of rice bran hydrolysates on migration, invasion and angiogenesis. Asian Pacific Journal of Tropical Biomedicine. 2021 Jul 1; 11(7): 317-3261.
  
• Chuenban C, Sombatsri A, Sribuhom T, Pornchoo C, Prawan A, Tontapha S, Amornkitbamrung V, Yenjai C. Knecorticosanones C-H from the fruits of: Knema globularia (Lam.) warb. RSC Advances. 2021;11(7):4097-4103.
  
• Kaewmeesri P, Kukongviriyapan V, Prawan A, Kongpetch S, Senggunprai L. Cucurbitacin B Diminishes Metastatic Behavior of Cholangiocarcinoma Cells by Suppressing Focal Adhesion Kinase. Asian Pac J Cancer Prev. 2021 Jan 1;22(1):219-225.
  
• Klungsaeng S, Kukongviriyapan V, Prawan A, Kongpetch S, Senggunprai L. Targeted modulation of FAK/PI3K/PDK1/AKT and FAK/p53 pathways by cucurbitacin B for the antiproliferation effect against human cholangiocarcinoma cells. American Journal of Chinese Medicine. 2020 Sep 9; 48(6): 1475-1489.
  
• Phusrisom S, Senggunprai L, Prawan A, Kongpetch S, Kukongviriyapan U, Thawornchinsombut S, Changsri R, Kukongviriyapan V. Rice bran hydrolysates induce immunomodulatory effects by suppression of chemotaxis, and modulation of cytokine release and cell-mediated cytotoxicity. Asian Pac J Trop Biomed 2020 Aug 17;10:470-8.
  
• Jaidee R, Kongpetch S, Senggunprai L, Prawan A, Kukongviriyapan U, Kukongviriyapan V. Phenformin inhibits proliferation, invasion, and angiogenesis of cholangiocarcinoma cells via AMPK-mTOR and HIF-1A pathways. Naunyn Schmiedebergs Arch Pharmacol. 2020 May 7.
  

    National Publication

• Jaidee R, Kongpetch S, Prawan A, Senggunprai L, Kukongviriyapan U, Kukongviriyapan V. Quercetin Enhances Phenformin in Inhibition of Cholangiocarcinoma Cell Growth. Srinagarind Med J. 2020 May-Jun;35(3):249-254.