ผศ.ดร.ภก.พิมาน โภคาทรัพย์
Assist. Prof. Piman Pocasap
Research Interest
- Natural Compounds in Cancer Therapy: Investigating the antimetastasis and antiproliferative effects of natural products on various cancers, including cholangiocarcinoma and hepatocellular carcinoma.
- Molecular Mechanisms of Cancer Progression: Studying molecular pathways like FAK/Src, PI3K-mTOR, and mechanisms such as apoptosis, autophagy, and chemoprevention in cancer.
- Bioactive Compounds and Functional Foods: Evaluating the antioxidant and anticancer properties of bioactive compounds from foods and natural sources, and exploring their chemopreventive potential.
Email :
pimapo@kku.ac.th
Publication
Last 5 years : 2022-2026
International Publication
- Pocasap P, Kongpetch S, Prawan A, Kaimuangpak K, Senggunprai L. Identification of Prognostic Factors in Esophageal Cancer Using Machine Learning: A Retrospective Study Based on the SEER Database. Journal of Clinical Medicine. 2026;15(8).
- Buranrat B, Sa-Ngiamwibool P, Prawan A, Kongpetch S, Pocasap P, Senggunprai L. Repurposing Rosiglitazone Induces Apoptosis Accompanied by Impaired Antioxidant Defense in Cholangiocarcinoma Cells: Findings from Proteomic and Functional Analyses. Pharmaceuticals. 2026;19(1).
- Pocasap P, Kaimuangpak K, Phukmee K, Prawan A, Kongpetch S, Senggunprai L. Unveiling the Anticancer Potential and Molecular Mechanisms of Fangchinoline Against Cholangiocarcinoma Using FTIR Microspectroscopy, In Vitro and In Silico Approaches. Integr Cancer Ther 2025; 24: 15347354251396513.
- Jaidee R, Pocasap P, Jusakul A, Senggunprai L, Prawan A, Hong JH, Heng HL, Kukongviriyapan V, Teh BT, Kongpetch S. Synergistic suppression of cholangiocarcinoma cells via DNA damage response and cell cycle arrest by dual targeting PARP and ATM in DNA damage repair pathway. Biomedicine and Pharmacotherapy 2025 Jun 18; 189: 118273.
- Jaidee R, Jusakul A, Pocasap P, Kukongviriyapan V, Senggunprai L, Prawan A, Loilome W, Titapun A, Jareanrat A, Thanasukarn V, Khuntikeo N, Namwat N, Chamgramol Y, Thanee M, Wichian P, Hong JH, Guan P, Heng HL, Pairojkul C, Teh BT, Kongpetch S. Establishment and genomic profiling of cholangiocarcinoma cells with functional characterization. Sci Rep 2025 Mar 13; 15: 8621; Published online.
- Pocasap P, Prawan A, Kongpetch S, Senggunprai L. Network pharmacology- and cell-based assessments identify the FAK/Src pathway as a molecular target for the antimetastatic effect of momordin Ic against cholangiocarcinoma. Heliyon. 2024 June; 10: e32352.
- Pocasap P, Tamprasit K, Rungsri T, Kaimuangpak K, Srisongkram T, Katekaew S, Kamwilaisak K, Puthongking P, Weerapreeyakul N. Pickering Emulsion of Oleoresin from Dipterocarpus alatus Roxb. ex G. Don and Its Antiproliferation in Colon (HCT116) and Liver (HepG2) Cancer Cells. Molecules. 2024 June; 29(11): Article number 2695.
- Mahaamnad N, Pocasap P, Kukongviriyapan V, Senggunprai L, Prawan A, Kongpetch S. Dual blockage of PI3K-mTOR and FGFR induced autophagic cell death in cholangiocarcinoma cells. Heliyon. 2024 May; 10: e31112.
- Pocasap P, Weerapreeyakul N, Wongpoomchai R. Thai Rat-Tailed Radish Prevents Hepatocarcinogenesis in Rats by Blocking Mutagenicity, Inducing Hepatic Phase II Enzyme, and Decreasing Hepatic Pro-Inflammatory Cytokine Gene Expression. Cancers. 2023 Mar 22;15(6):1906.
- Kaewmeesri P, Pocasap P, Kukongviriyapan V, Prawan A, Kongpetch S, Senggunprai L. Anti-metastatic Potential of Natural Triterpenoid Cucurbitacin B Against Cholangiocarcinoma Cells by Targeting Src Protein. Integr Cancer Ther 2022 Sep 27; 21: 15347354221124861.
National Publication
- Boonloh K, Pocasap P. Kongpetch S, Pannangpetch P, Kukongviriyapan V. Unveiling the Mechanism of Madecassic Acid in Nonalcoholic Fatty Liver Disease: A Network Pharmacology and Experimental Validation. J. Basic. App. Pharmacol. 2024 Jul-Dec;4(2):108-120.