Scopus Author Profile

ผศ.ดร.ภญ.ศริญญา คงเพชร

Assist. Prof. Sarinya Kongpetch

Research Interest :

• Precision medicine
• Pharmacogenomics
• Cancer genomics
• Molecular oncology
• Tyrosine Kinase Inhibitor
• DNA Damage and Repair

Email : sarinyako@kku.ac.th

Publication (Last 5 years : 2020-2024)

    International Publication

• Pocasap P, Prawan A, Kongpetch S, Senggunprai L. Network pharmacology- and cell-based assessments identify the FAK/Src pathway as a molecular target for the antimetastatic effect of momordin Ic against cholangiocarcinoma. Heliyon. 2024 June; 10: e32352.
  
• Mahaamnad N, Pocasap P, Kukongviriyapan V, Senggunprai L, Prawan A, Kongpetch S. Dual blockage of PI3K-mTOR and FGFR induced autophagic cell death in cholangiocarcinoma cells. Heliyon. 2024 May; 10: e31112.
  
• Janthamala S, Promraksa B, Thanee M, Duenngai K, Jusakul A, Kongpetch S, Kraiklang R, Thanee K, Pinlaor P, Namwat N, Saya H, Techasen A. Anticancer properties and metabolomic profiling of Shorea roxburghii extracts toward gastrointestinal cancer cell lines. BMC Complement Med Ther. 2024 Apr 30;24(1):178.
  
• Khosla D, Misra S, Chu PL, Guan P, Nada R, Gupta R, Kaewnarin K, Ko TK, Heng HL, Srinivasalu VK, Kapoor R, Singh D, Klanrit P, Sampattavanich S, Tan J, Kongpetch S, Jusakul A, Teh BT, Chan JY, Hong JH. Cholangiocarcinoma: Recent Advances in Molecular Pathobiology and Therapeutic Approaches. Cancers (Basel) 2024; 16.
  
• Hong JH, Yong CH, Heng HL, Chan JY, Lau MC, Chen J, Lee JY, Lim AH, Li Z, Guan P, Chu PL, Boot A, Ng SR, Yao X, Wee FYT, Lim JCT, Liu W, Wang P, Xiao R, Zeng X, Sun Y, Koh J, Kwek XY, Ng CCY, Klanrit P, Zhang Y, Lai J, Tai DWM, Pairojkul C, Dima S, Popescu I, Hsieh SY, Yu MC, Yeong J, Kongpetch S, Jusakul A, Loilome W, Tan P, Tan J, Teh BT. Integrative multiomics enhancer activity profiling identifies therapeutic vulnerabilities in cholangiocarcinoma of different etiologies. Gut. 2023 Nov 24:gutjnl-2023-330483. doi: 10.1136/gutjnl-2023-330483. Online ahead of print.
  
• Oeurn K, Jusakul A, Jaidee R, Kukongviriyapan V, Senggunprai L, Prawan A, Kongpetch S. FGF10/FGFR2 Signaling: Therapeutically Targetable Vulnerability in Ligand-responsive Cholangiocarcinoma Cells. In Vivo. 2023 Jul-Aug;37(4):1628-1637.
  
• Sirithawat P, Jusakul A, Kongpetch S, Thanee M, Srichanchara P, Panjaroensak S, Kimawaha P, Janthamala S, Aphivatanasiri C, Techasen A. Alteration of STK11 Expression Associated With Cholangiocarcinoma Progression. In Vivo. 2023 Jul-Aug;37(4):1638-1648. doi: 10.21873/invivo.13249.
  
• Malikrong P, Prawan A,Kongpetch S, Senggunprai L. Momordin ic triggers mitochondria-mediated apoptosis of cholangiocarcinoma cells and enhances the efficacy of conventional chemotherapeutic drugs. Farmacia. 2023 Feb;71(3):518–525.
  
• Butsri S, Kukongviriyapan V, Senggunprai L, Kongpetch S, Prawan A. 13-cis-retinoic acid inhibits the self-renewal, migration, invasion and adhesion of cholangiocarcinoma cells. Int J Mol Med 2023; 51. Published online 2023 Jan 21.
  
• Kaewmeesri P, Pocasap P, Kukongviriyapan V, Prawan A, Kongpetch S, Senggunprai L. Anti-metastatic Potential of Natural Triterpenoid Cucurbitacin B Against Cholangiocarcinoma Cells by Targeting Src Protein. Integr Cancer Ther 2022 Sep 27; 21: 15347354221124861.
  
• Senggunprai L, Kukongviriyapan V, Prawan A, Kongpetch S. Epidermal growth factor receptor as a potential target of momordin Ic to promote apoptosis of cholangiocarcinoma cells. J Pharm Pharmacol . 2022 Jul 15;74(7):996-1005.
  
• Butsri S, Kukongviriyapan V, Senggunprai L, Kongpetch S, Prawan A. All-trans-retinoic acid induces RARB-dependent apoptosis via ROS induction and enhances cisplatin sensitivity by NRF2 downregulation in cholangiocarcinoma cells. Oncol Lett. 2022 Jun;23(6):179.
  
• Jaidee R, Kukongviriyapan V, Senggunprai L, Prawan A, Jusakul A, Laphanuwat P, Kongpetch S. Inhibition of FGFR2 enhances chemosensitivity to gemcitabine in cholangiocarcinoma through the AKT/mTOR and EMT signaling pathways. Life Sci. 2022 May 1; 296: 120427.
  
• Tessiri S, Techasen A, Kongpetch S, Namjan A, Loilome W, Chan-On W, Thanan R, Jusakul A. Therapeutic targeting of ARID1A and PI3K/AKT pathway alterations in cholangiocarcinoma. PeerJ. 2022 Jan 13; 10: e12750.
  
• Laphanuwat P, Kongpetch S, Senggunprai L, Prawan A, Kukongviriyapan V. Licochalcone A Induces Cholangiocarcinoma Cell Death Via Suppression of Nrf2 and NF-kappaB Signaling Pathways. Asian Pac J Cancer Prev. 2022 Jan 1; 23: 115-123.
  
• Wandee J, Srinontong P, Prawan A, Senggunprai L, Kongpetch S, Yenjai C, Kukongviriyapan V. Derrischalcone suppresses cholangiocarcinoma cells through targeting ROS-mediated mitochondrial cell death, Akt/mTOR, and FAK pathways. Naunyn Schmiedebergs Arch Pharmacol. 2021 Sep;394(9):1929-1940.
  
• Janthamala S, Jusakul A, Kongpetch S, Kimawaha P, Klanrit P, Loilome W, Namwat N, Techasen A. Arctigenin inhibits cholangiocarcinoma progression by regulating cell migration and cell viability via the N-cadherin and apoptosis pathway. Naunyn Schmiedebergs Arch Pharmacol . 2021 Jul 20.
  
• Phusrisom S, Senggunprai L, Prawan A, Kongpetch S, Kukongviriyapan U, Thawornchinsombut S, Siriamornpun S, Chumroenphat T, Changsri R, Kukongviriyapan V. Anti-tumor activity of rice bran hydrolysates on migration, invasion and angiogenesis. Asian Pacific Journal of Tropical Biomedicine. 2021 Jul 1; 11(7): 317-3261.
  
• Wintachai P, Lim JQ, Techasen A, Lert-Itthiporn W, Kongpetch S, Loilome W, Chindaprasirt J, Titapun A, Namwat N, Khuntikeo N, Jusakul A. Diagnostic and Prognostic Value of Circulating Cell-Free DNA for Cholangiocarcinoma. Diagnostics (Basel) . 2021 May 30;11(6):999.
  
• Goyal L, Kongpetch S, Crolley V,E, Bridgewater J. Targeting FGFR inhibition in cholangiocarcinoma. Cancer Treat Rev. 2021 Apr;95:102170. Epub 2021 Feb 26.
  
• Kaewmeesri P, Kukongviriyapan V, Prawan A, Kongpetch S, Senggunprai L. Cucurbitacin B Diminishes Metastatic Behavior of Cholangiocarcinoma Cells by Suppressing Focal Adhesion Kinase. Asian Pac J Cancer Prev. 2021 Jan 1;22(1):219-225.
  
• Klungsaeng S, Kukongviriyapan V, Prawan A, Kongpetch S, Senggunprai L. Targeted modulation of FAK/PI3K/PDK1/AKT and FAK/p53 pathways by cucurbitacin B for the antiproliferation effect against human cholangiocarcinoma cells. American Journal of Chinese Medicine. 2020 Sep 9; 48(6): 1475-1489.
  
• Phusrisom S, Senggunprai L, Prawan A, Kongpetch S, Kukongviriyapan U, Thawornchinsombut S, Changsri R, Kukongviriyapan V. Rice bran hydrolysates induce immunomodulatory effects by suppression of chemotaxis, and modulation of cytokine release and cell-mediated cytotoxicity. Asian Pac J Trop Biomed 2020 Aug 17;10:470-8.
  
• Jaidee R, Kongpetch S, Senggunprai L, Prawan A, Kukongviriyapan U, Kukongviriyapan V. Phenformin inhibits proliferation, invasion, and angiogenesis of cholangiocarcinoma cells via AMPK-mTOR and HIF-1A pathways. Naunyn Schmiedebergs Arch Pharmacol. 2020 May 7.
  
• Kongpetch S, Jusakul A, Lim JQ, Ng CCY, Chan JY, Rajasegaran V, Lim TH, Lim KH, Choo SP, Dima S, Popescu I, Duda DG, Kukongviriyapan V, Khuntikeo N, Pairojkul C, Rozen SG, Tan P, Teh BT. Lack of Targetable FGFR2 Fusions in Endemic Fluke-Associated Cholangiocarcinoma. JCO Glob Oncol. 2020 Apr;6:628-38.
  

    National Publication

• Jaidee R, Kongpetch S, Prawan A, Senggunprai L, Kukongviriyapan U, Kukongviriyapan V. Quercetin Enhances Phenformin in Inhibition of Cholangiocarcinoma Cell Growth. Srinagarind Med J. 2020 May-Jun;35(3):249-254.